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News
Anthrax may be ally in cancer war
www.world-science.net
The toxin has been shown to be fairly selective in targeting melanoma, or skin cancer, cells, according to Stephen Leppla of the National ...
Toxin Targets Tumor Blood Vessels - National Cancer Institute
www.cancer.gov
The ability to target anthrax toxin to tumors so that healthy tissue is spared depends on a unique property of the toxin, explained study leader Stephen Leppla, Ph.D., of the National Institute of Allergy and Infectious Diseases.
Publication of Gisou van der Goot & group in Cell Reports – NCCR in...
nccr-chembio.ch
A publication of Laurence Abrami, Lucia Brandi, Mahtab Moayeri, Michael J. Brown, Bryan A. Krantz, Stephen H. Leppla, and F. Gisou van der ...
Telephone & Addresses
Stephen Leppla, Bethesda, US, Herkos Ct
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Stephen Leppla, Centerburg, US, Larimore Rd
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Stephen Leppla, Mount Vernon, US, Ames St
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Stephen B Leppla, 75, Mount Vernon, US, Airport Rd
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Network Profiles
Stephen H. Leppla | Semantic Scholarwww.semanticscholar.org › author › Stephen-H.-Leppla
www.semanticscholar.org
Stephen H. Leppla. CLAIM AUTHOR PAGE. Publications29. Citations814. Highly Influential Citations56. Publications; Influence. 29 results. Sort ...
Interests
Crystal structure for anthrax-cell binding complex | EurekAlert!...
www.eurekalert.org
Researchers have determined the crystal structure of the binding complex between anthrax toxin and one of its host receptors. The studies offer new leads for...
Effective, Safe Anthrax Vaccine Can Be Grown In Tobacco Plants
www.sciencedaily.com
Enough anthrax vaccine to inoculate everyone in the United States could be grown in one acre of tobacco in one year. The new, cost-effective production method...
Stephen H. Leppla - Patents
www.freshpatents.com
Stephen H. Leppla patents Recent bibliographic sampling of Stephen H. Leppla patents listed/published in the public domain by the USPTO (USPTO Patent …
Study says modified anthrax might fight cancer
www.smh.com.au
... said Dr Stephen Leppla, an NIH scientist and co-author of the study. In theory, the new toxin should work on all or almost all forms of cancer, ...
Business Profiles
patentbuddy: Stephen H Leppla
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT, Bethesda, MD, US
patentbuddy: Stephen Leppla
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT, Bethesda, MD, US
Education
classmates: Stephen Leppla
Wooster High School, Wooster, OH,
Anthrax3
www-ssrl.slac.stanford.edu
Eugenio Santelli, Laurie A. Bankston, Stephen H. Leppla & Robert C. Liddington ... http://www-ssrl.slac.stanford.edu/research/highlights_archive/anthrax3.html.
Bad news
Stephen Leppla Obituary - Mount Vernon, Ohio - Tributes.com
www.tributes.com
At Tributes.com we believe that Every Life has a Story that deserves to be told and preserved.. Tributes.com is the online source for current local and national obituary news and a supportive community where friends and family can come together during times of loss and grieving to honor the memories of their loved ones with lasting personal tributes.
Books & Literature
Handbook of Proteolytic Enzymes, Volume 1 - Google Books
books.google.cz
Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on...
Guidebook to Protein Toxins and Their Use in Cell Biology - Google...
books.google.de
Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of
National Institute of Dental Research Programs - National Institute...
books.google.cz
... Paul Kolenbrander, Paul E. Kousvelari, Eleni Lan, Michael S. Le Thi, Bich-Thuy Leppla, Stephen H Leppla, Stephen H Li, Shou-Hua Li, Shou-Hua Loe, Harald ...
New Developments and New Applications in Animal Cell Technology:...
books.google.de
Acknowledgements We are grateful to Wim van de Yen, John Creemers, and Stephen Leppla for mat al, Gary Thomas, Nabil Seidah, Anton Roebroek and ...
Related Documents
Anthrax LFn-PA Hybrid Antigens: Biochemistry, Immunogenicity, and...
benthamopen.com
Anthrax LFn-PA Hybrid Antigens: Biochemistry, Immunogenicity, and Protection Against Lethal Ames Spore Challenge in Rabbits#
UNCLASSIFIED J SgCURITý CLASSIrJCATION : …
www.dtic.mil
UNCLASSIFIED J "SgCURITý CLASSIrJCATION OF T1.IS PGE "we Dete r.•): ... Authors: Viloya S. Allured , Lisa M. Case , Stephen H. Leppla and David B. McKay#
Shihui Liu, G. Todd Milne, Jeffrey G. Kuremsky, Gerald R. Fink,...
pdfslide.us
Identification of the Proteins Required for Biosynthesis of Diphthamide, the Target of Bacterial ADP-Ribosylating Toxins on Translation Elongation Factor 2...
The Exotoxin of P. aeruginosa: A Proenzyme Having an Unusual ...
www.dtic.mil
Stephen H. Leppla, Laura A./'MuehlVOna G./arn. /Marti. 9. PERFORMING ORGANIZATION NAME AND ADDRESS PROGRAM ELEMENT. PROJECT, TASK.
Scientific Publications
Anthrax Toxin - an overview | ScienceDirect Topics
www.sciencedirect.com
Stephen H. Leppla, in The Comprehensive Sourcebook of Bacterial Protein Toxins (Third Edition), Actions of the lethal and edema toxins in animals. Anthrax toxin was first recognized by noting the edema caused by intradermal injection of bacterial culture supernatant or plasma of infected animals (Smith et al., 1955).Fractionation showed that this effect was due to the mixture of ...
Late Treatment with a Protective Antigen-Directed Monoclonal JStor
www.jstor.org
Jing Feng,1 Steven M. Banks,1 Stephen H. Leppla,2 and Peter Q. Eichacker1. 'Critical Care Medicine Department, Clinical Center, and National Institute of ...
Stephen H. Leppla, Ph.D. | NIH: National Institute of ...
www.niaid.nih.gov
Stephen H. Leppla, Ph.D. Chief, Microbial Pathogenesis Section. Contact Information. Stephen H. Leppla, Ph.D. Major Areas of Research. Structure-function relationships in bacterial protein toxins and the roles of toxins and other virulence factors in contributing to bacterial pathogenesis;
Collaborators - Bezrukov Lab: Section on Molecular ...
www.nichd.nih.gov
Dr. Stephen H. Leppla, Microbial and Pathogenesis Section, NIAID Dr. Kamran C. Melikov, Laboratory of Cellular and Molecular Biophysics, PPB/NICHD Dr. Caroline Philpott, Genetics and Metabolism Section, Liver Diseases Branch, NIDDK
Publications
Publications Authored by Stephen H Leppla | PubFacts
www.pubfacts.com
Publications Authored by Stephen H Leppla
Toxins | Free Full-Text | Tumor Targeting and Drug Delivery by...
www.mdpi.com
Anthrax toxin is a potent tripartite protein toxin from Bacillus anthracis. It is one of the two virulence factors and causes the disease anthrax. The...
Effects of Lectins on the Interaction of Diphtheria Toxin with...
www.worldcat.org
Get this from a library! Effects of Lectins on the Interaction of Diphtheria Toxin with Mammalian Cells.. [John L Middlebrook; Rebecca B Dorland; Stephen H Leppla ...
Reports & Statements
Bacillus cereus non-haemolytic enterotoxin activates the NLRP3...
www.nature.com
... National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MDUSA. Stephen H. Leppla. Authors.
nature.com search
www.nature.com
nature.com search. Login / Sign up. Showing 1–15 of 15 results. Search. advanced. Authors: ... Stephen H Leppla, R John Collier, Robert C Liddington & Lewis C Cantley.
Anthrax's line of attack questioned | Nature
www.nature.com
… bacterium may not hijack immune cells after all.
Miscellaneous
WO A3 - Anthrax lethal factor is a mapk kinase ...
patents.google.com
Stephen Leppla Craig Webb George Vande Woude Original Assignee Nicholas Duesbery Stephen Leppla Us Gov Health & Human Serv Craig Webb George Vande Woude Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed ...
Stephen H. Leppla, PhD - Kerafast
www.kerafast.com
Kerafast offers difficult-to-access bioresearch materials from prominent institutions around the world.
ANTHRAX TOXIN Stephen H. Leppla, Bruce E. Ivins, and John W ...
www.dtic.mil
(0} II 00 ANTHRAX TOXIN Stephen H. Leppla, Bruce E. Ivins, and John W. Ezzell, Jr. Bacteriology Division U.S. Army Medical Research Institute of Infectious
Stephen H. Leppla, Bethesda US - Patent applications
www.patentsencyclopedia.com
Patent application number Description Published; : Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts ...
Pathophysiological Actions of the Anthrax Toxins - Stephen Leppla
grantome.com
Anthrax toxin protective antigen (PA, 83 kDa) binds to receptors on the surface of mammalian cells, is cleaved by the cell surface protease furin, and then bind...
PPT - Shihui Liu, G. Todd Milne, Jeffrey G. Kuremsky, Gerald R. Fink,...
www.slideserve.com
Identification of the Proteins Required for Biosynthesis of Diphthamide, the Target of Bacterial ADP-Ribosylating Toxins on Translation Elongation Factor
Anti-tumor activity of anthrax toxin variants that Oncotargetwww.oncotarget.com › ...
www.oncotarget.com
Oncotarget | https://doi.org oncotarget Shihui Liu, Qian Ma, Rasem Fattah, Thomas H. Bugge, Stephen H. Leppla.
Just a moment...
www.jimmunol.org
Alexandra Duverger, Raymond J. Jackson, Frederick W. van Ginkel, Romy Fischer, Angela Tafaro, Stephen H. Leppla, Kohtaro Fujihashi, Hiroshi Kiyono, Jerry ...
Anthrax Fusion Protein Therapy of Cancer | Bentham Science
www.eurekaselect.com
Anthrax Fusion Protein Therapy of Cancer George F. Vande Woude and Stephen H. Leppla ... Anthrax Fusion, Protein Therapy, ...
Anthrax Antigen
biology.kenyon.edu
... Shihui Liu, and Stephen H. Leppla Identification of a Receptor-Binding Region Within Domain IV of the Protective Antigen Component of Anthrax Toxin. I ...
Citations to Development of an improved vaccine for JCIwww.jci.org › articles › view › citations
www.jci.org
Stephen H. Leppla, … , Rachel Schneerson, Joseph Shiloach. Stephen H. Leppla, … , Rachel Schneerson, Joseph Shiloach. Published July 15, Citation ...
Federal Register, Volume 78 Issue 147 (Wednesday, July 31, 2013)
www.govinfo.gov
[Federal Register Volume 78, Number 147 (Wednesday, July 31, 2013)] ... Mahtab Moayeri, Nolan K. Maier, Stephen H. Leppla ...
Novel Protein Targeted Therapy of Metastatic Melanoma | Bentham...
www.eurekaselect.com
Metastatic melanoma patients have a dismal prognosis with poor responsiveness to chemotherapy, radiation therapy and current immunotherapy regime...
STOCK Antxr1/J - The Jackson Laboratory
www.jax.org
Donating Investigator. Stephen H. Leppla, National Institute of Allergy and Infectious Diseases. Read More +. Genetic overview. Genetic Background ...
How Anthrax Kills: Toxins Damage Liver and Heart | Live Science
www.livescience.com
Infection with anthrax is deadly, but it isn't the bacteria themselves that kill. Rather, the toxins the bacteria produce damage human cells. Now a new study...
Molecular Genetics and Pathogenesis of Anthrax - Stephen ...
grantome.com
See 54 grants from Stephen Leppla See grants from National Institute of Allergy and Infectious Diseases
Novel Anthrax Vaccine - MedicineNet
www.medicinenet.com
Sep 02, · The discovery that toxins released by the bacteria do not behave as previously believed should redirect approaches to anthrax drug design, notes NIAID Senior Investigator Stephen Leppla, Ph.D., whose research is published in today's issue of the "Journal of Clinical Investigation".
DEFINE_ME
ajp.amjpathol.org
Stephen H. Leppla. Search for articles by this author Affiliations. National Institute of Allergy and Infectious Diseases, Office of Research Services, ...
ETOX Scientific Program
etox14.u-strasbg.fr
Stephen LEPPLA N°4.08 CMG2 IS THE MAJOR RECEPTOR MEDIATING LETHALITY OF ANTHRAX TOXIN IN VIVO, WHEREAS TEM8 PLAYS ONLY A MINOR ...
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